Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920373 | 0.81 | KMT2A (0.53) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL1414894 | 0.72 | NOS1 (0.51) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL2664133 | 0.72 | TSHR (0.52) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL19124507 | 0.70 | EPHX1 (0.38) | MEN1KMT2AHPGDTSHRPOLB | |
| SCHEMBL10436784 | 0.70 | KMT2A (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL4188566 | 0.70 | SCN4A (0.45) | KMT2ARAB9ASMN1; SMN2TSHRHTT | |
| SCHEMBL2659282 | 0.70 | KMT2A (0.56) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL5787901 | 0.70 | KDM4C (0.37) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL162880 | 0.68 | KMT2A (0.58) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL1058997 | 0.68 | CYP1A2 (0.49) | HPGDSMN1; SMN2MAPTJMJD6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622876-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099157-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-18 | — | — | WO | disclosed |