SCHEMBL5769381

SCHEMBL5769381

O=C(Br)C1CCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28921535 1.00
SCHEMBL6143078 0.81 NOS2 (0.52)
SCHEMBL6143295 0.81 NOS2 (0.52)
SCHEMBL6143108 0.81 NOS2 (0.52)
SCHEMBL4684876 0.79
SCHEMBL1372794 0.79
SCHEMBL92737 0.79
SCHEMBL8584758 0.79
SCHEMBL1061189 0.79
SCHEMBL239908 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7129350-B2 Coupling process and intermediates useful for preparing cephalosporins PFIZER, INC. (US) 2006-10-31 US disclosed
EP-1339723-B1 PROCESS AND ESTER DERIVATIVES USEFUL FOR PREPARATION OF CEPHALOSPORINS PFIZER PROD INC (US) 2006-03-08 EP disclosed
US-20040267008-A1 Process and ester derivatives useful for preparation of cephalosporins PFIZER INC 2004-12-30 US disclosed
US-20040167327-A1 Coupling process and intermediates useful for preparing cephalosporins ZOETIS SERVICES LLC 2004-08-26 US disclosed
EP-1339723-A1 PROCESS AND ESTER DERIVATIVES USEFUL FOR PREPARATION OF CEPHALOSPORINS Pfizer Products Inc. (US) 2003-09-03 EP disclosed
US-20020198375-A1 Coupling process and intermediates useful for preparing cephalosporins PFIZER INC. 2002-12-26 US disclosed
US-20020099205-A1 Process and ester derivatives useful for preparation of cephalosporins PFIZER INC. 2002-07-25 US disclosed
WO-2002046199-A1 PROCESS AND ESTER DERIVATIVES USEFUL FOR PREPARATION OF CEPHALOSPORINS PFIZER PRODUCTS INC. (US) 2002-06-13 WO disclosed