Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5769741 | 0.91 | CNR1 (0.48) | CNR1MAPTCNR2 | |
| SCHEMBL5769761 | 0.89 | CNR1 (0.47) | CNR1LMNAHTTCNR2 | |
| SCHEMBL5098463 | 0.77 | CNR1 (0.53) | CNR1ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL5105634 | 0.68 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL27523649 | 0.68 | HTR2A (0.53) | HTT | |
| SCHEMBL5769555 | 0.68 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL5113066 | 0.67 | CNR1 (0.53) | CNR1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5103007 | 0.67 | CNR1 (0.60) | CNR1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5105716 | 0.66 | LMNA (0.52) | CNR1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5111418 | 0.66 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716142-A2 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEROF | Sanofi-Aventis (FR) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080357-A2 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEROF | SANOFI-AVENTIS (FR) | 2005-09-01 | — | — | WO | disclosed |