Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 15/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646421 | 0.82 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL27648784 | 0.81 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL5645912 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5794421 | 0.78 | PTGS2 (0.45) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL5647926 | 0.77 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5769728 | 0.77 | PTGS2 (0.44) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL5770151 | 0.72 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL6093841 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6092243 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5768066 | 0.69 | PTGS2 (0.70) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631562-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | Pharmacia Corporation (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1615905-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | Pharmacia Corporation (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004087687-A1 | CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087686-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |