SCHEMBL5769840

SCHEMBL5769840

O=C(NC1CC2CCC1C2)c1nn(-c2ccc(Cl)cc2Cl)c(Oc2ccc(Cl)cc2)c1CNC1CCC1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 13/20 0.49
CNR2 P34972 11/20 0.45
OPRL1 P41146 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5766548 0.98 CNR1 (0.49) CNR1CNR2OPRL1
SCHEMBL5768413 0.89 CNR1 (0.49) CNR1CNR2
SCHEMBL5768210 0.86 CNR1 (0.47) CNR1CNR2
SCHEMBL6770110 0.85 CNR1 (0.50) CNR1CNR2
SCHEMBL6765994 0.83 CNR1 (0.48) CNR1CNR2
SCHEMBL6769589 0.83 CNR1 (0.47) CNR1CNR2
SCHEMBL5770166 0.83 CNR1 (0.53) CNR1CNR2
SCHEMBL5766304 0.82 CNR2 (0.51) CNR1CNR2OPRL1
SCHEMBL5769099 0.82 CNR2 (0.51) CNR1CNR2OPRL1
SCHEMBL5769838 0.81 OPRL1 (0.43) CNR1CNR2OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040235926-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC. 2004-11-25 US claimed
EP-1622876-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF Pfizer Products Inc. (US) 2006-02-08 EP disclosed
US-20040235926-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC. 2004-11-25 US disclosed
WO-2004099157-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER PRODUCTS INC. (US) 2004-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235926-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 CNR1 1/4885CNR2 2/4885OPRL1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.