Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290791 | 0.88 | POLB (0.70) | MGLLPOLBCA12CA1CA2 | |
| Bicarbonate SCHEMBL25171118 | 0.82 | POLB (0.64) | MGLLPOLBSMN1; SMN2CA12CA1 | |
| SCHEMBL40679 | 0.80 | POLB (0.61) | MGLLPOLBSMN1; SMN2F2PLG | |
| SCHEMBL598078 | 0.80 | MGLL (0.50) | MGLLFAAHPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL1908550 | 0.80 | MGLL (0.50) | MGLLFAAHPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL97876 | 0.79 | HDAC6 (0.67) | MGLLFAAHPOLBHDAC7MEN1 | |
| SCHEMBL22320218 | 0.78 | MGLL (1.00) | MGLLFAAHENPP2F2PLG | |
| SCHEMBL28548456 | 0.78 | CA12 (0.59) | MGLLFAAHPOLBCA12CA1 | |
| SCHEMBL95681 | 0.78 | HDAC7 (0.46) | MGLLFAAHPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL95580 | 0.78 | POLB (0.50) | MGLLFAAHPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625130-A2 | HIV INTEGRASE INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004096807-A2 | HIV INTEGRASE INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2004-11-11 | — | — | WO | disclosed |