Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CNOT7 | Q9UIV1 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947257 | 0.81 | POLB (0.83) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL6385813 | 0.78 | POLB (0.69) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL5772602 | 0.78 | DPP4 (0.44) | POLBHIF1ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5719179 | 0.77 | POLB (0.66) | POLBHIF1ASMN1; SMN2CNOT7ALDH1A1 | |
| SCHEMBL5773292 | 0.77 | BRD4 (0.61) | POLBSMN1; SMN2ADORA2BRXFP1CNOT7 | |
| SCHEMBL1944712 | 0.76 | POLB (0.70) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL3112709 | 0.75 | POLB (0.68) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL2961214 | 0.74 | POLB (0.64) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL11014928 | 0.74 | POLB (0.83) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL3116289 | 0.74 | POLB (0.86) | POLBHIF1ASMN1; SMN2ADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | POLB 4529/4885HIF1A 2615/4885SMN1; SMN2 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.