Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555650 | 0.84 | HIF1A (0.57) | DPP4HIF1APOLBALDH1A1HPGD | |
| SCHEMBL5770135 | 0.83 | DPP4 (0.66) | DPP4FAPCHRM1 | |
| Hydrochloric Acid SCHEMBL5771703 | 0.83 | DPP4 (0.65) | DPP4FAPCHRM1 | |
| SCHEMBL6384057 | 0.80 | POLB (0.45) | DPP4HIF1APOLBALDH1A1HPGD | |
| SCHEMBL5718898 | 0.80 | LMNA (0.54) | HIF1APOLBALDH1A1LMNATP53 | |
| SCHEMBL2960923 | 0.79 | DPP4 (0.45) | DPP4HIF1APOLBALDH1A1LMNA | |
| SCHEMBL5771106 | 0.78 | POLB (0.67) | HIF1APOLBALDH1A1HPGDMAPK1 | |
| SCHEMBL2965812 | 0.77 | POLB (0.42) | DPP4HIF1APOLBALDH1A1LMNA | |
| SCHEMBL28749929 | 0.74 | HIF1A (0.62) | HIF1APOLBALDH1A1HPGDLMNA | |
| SCHEMBL555012 | 0.72 | HIF1A (0.63) | HIF1APOLBALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | DPP4 1/4885HIF1A 2615/4885POLB 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.