Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 16/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5772915 | 0.98 | NPY5R (0.74) | NPY5RMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5774640 | 0.85 | NPY5R (0.57) | NPY5RKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23815346 | 0.76 | NPY5R (0.63) | NPY5RMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5775421 | 0.74 | NPY5R (0.77) | NPY5RMEN1KMT2AHRH4MAOB | |
| SCHEMBL5771155 | 0.73 | NPY5R (0.78) | NPY5RMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5772544 | 0.73 | NPY5R (0.82) | NPY5R | |
| Hydrochloric Acid SCHEMBL5771749 | 0.72 | NPY5R (0.73) | NPY5RMEN1KMT2AHRH4MAOB | |
| Hydrochloric Acid SCHEMBL5773817 | 0.72 | NPY5R (0.76) | NPY5RMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5772581 | 0.72 | NPY5R (0.80) | NPY5R | |
| SCHEMBL5404393 | 0.68 | MEN1 (0.53) | NPY5RMEN1KMT2AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |