Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283529 | 0.74 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5773959 | 0.74 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5776097 | 0.74 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL15029205 | 0.72 | MAPK1 (0.42) | MAPK14 | |
| SCHEMBL5772128 | 0.71 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL5774664 | 0.71 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5773551 | 0.70 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL5774872 | 0.70 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL40860 | 0.70 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL5773224 | 0.70 | MAPK14 (0.57) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370559-B1 | TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS | PFIZER PROD INC (US) | 2006-04-19 | — | — | EP | disclosed |