Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.61 |
| ▸ | MAOB | P27338 | 12/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | CALML3 | P27482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SDHA | P31040 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771475 | 1.00 | F10 (0.61) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL13357836 | 0.93 | MAOB (0.54) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL3197103 | 0.90 | F10 (0.65) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL6629866 | 0.90 | F10 (0.65) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL3523994 | 0.90 | F10 (0.59) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL3523989 | 0.90 | F10 (0.59) | F10MAOBMAOACALML3LMNA | |
| Tert-Butyl Formate SCHEMBL27604230 | 0.89 | F10 (0.54) | F10MAOBMAOACALML3LMNA | |
| Hydrochloric Acid SCHEMBL6610394 | 0.89 | F10 (0.64) | F10MAOBMAOACALML3LMNA | |
| Hydrochloric Acid SCHEMBL6610396 | 0.89 | F10 (0.64) | F10MAOBMAOACALML3LMNA | |
| SCHEMBL13404010 | 0.88 | F10 (0.58) | F10MAOBMAOACALML3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349853-B1 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | PHARMACIA & UPJOHN CO LLC (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6869965-B2 | Such as 2-methylpropyl-(4-bromo-3-fluorophenyl)carbamate | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-22 | — | — | US | disclosed |
| US-20040215017-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | PHARMACIA & UPJOHN COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | LABORATORIOS VITA, S.A. (ES) | 2004-07-29 | — | — | US | disclosed |
| EP-1401834-A1 | NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | LABORATORIOS VITA, S.A. (ES) | 2004-03-31 | — | — | EP | disclosed |
| US-6689769-B2 | BACTERICIDES | PHARMACIA & UPJOHN COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1349853-A2 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | Pharmacia & Upjohn Company (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20030013737-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | PHARMACIA & UPJOHN COMPANY | 2003-01-16 | — | — | US | disclosed |
| WO-2003002560-A1 | NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | LABORATORIOS VITA, S.A. (ES) | 2003-01-09 | — | — | WO | disclosed |
| WO-2002059116-A2 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013737-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | BRD7, BRD1, NQO2 | F10 3680/4885MAOB 1965/4885MAOA 2041/4885 |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | OXA1L, Q6ZSR9, PGC | F10 1608/4885MAOB 711/4885MAOA 697/4885 |
| US-20040215017-A1 | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections | BRD7, BRD1, NQO2 | F10 3680/4885MAOB 1965/4885MAOA 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.