Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | GMPS | P49915 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | PI4KA | P42356 | 3/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL771467 | 0.91 | ADORA3 (0.59) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL622587 | 0.89 | ADORA3 (0.49) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL8623729 | 0.85 | ADORA3 (0.45) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL5773666 | 0.83 | EHMT1 (0.43) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL27389905 | 0.83 | ADORA3 (0.44) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL10708354 | 0.83 | ADORA3 (0.48) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL13269086 | 0.81 | ADORA3 (0.48) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL1434125 | 0.81 | ADORA3 (0.48) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL25389234 | 0.81 | SLC28A2 (0.43) | ADORA3ADORA2AGMPSADORA1PI4KA | |
| SCHEMBL932845 | 0.81 | ADORA3 (0.49) | ADORA3ADORA2AGMPSADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611254-A2 | COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP | Roche Diagnostics GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004092412-A2 | COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP | ROCHE DIAGNOSTICS GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |