⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600073 | 0.83 | — | — | |
| SCHEMBL9389351 | 0.83 | — | — | |
| SCHEMBL7462125 | 0.81 | — | — | |
| SCHEMBL20236961 | 0.81 | — | — | |
| SCHEMBL7461191 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL27396824 | 0.74 | — | — | |
| SCHEMBL27847537 | 0.74 | — | — | |
| SCHEMBL27847527 | 0.74 | — | — | |
| SCHEMBL97635 | 0.74 | — | — | |
| SCHEMBL20425296 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | claimed |
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| US-10105380-B2 | Glycoclusters and their pharmaceutical use as antibacterials | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-10-23 | — | — | US | disclosed |
| EP-3049426-B1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | CENTRE NAT RECH SCIENT (FR) | 2017-11-01 | — | — | EP | disclosed |
| US-20160287620-A1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | UNIVERSITE DE MONTPELLIER (FR) | 2016-10-06 | — | — | US | disclosed |
| EP-3049426-A1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | Centre National De La Recherche Scientifique (FR) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015040209-A1 | GLYCOCLUSTERS AND THEIR PHARMACEUTICAL USE AS ANTIBACTERIALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-26 | — | — | WO | disclosed |
| EP-2851371-A1 | Glycoclusters and their pharmaceutical use as antibacterials | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-03-25 | — | — | EP | disclosed |
| EP-1226144-B1 | ALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE | HOFFMANN LA ROCHE (CH) | 2006-12-27 | — | — | EP | disclosed |
| US-6642241-B1 | Alkylamino- substituted dihydropyrimido-(4,5-d)pyrimidinone derivatives, inhibitors of p38, | SYNTEX (U.S.A.) LLC | 2003-11-04 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-1226144-A1 | ALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001029041-A1 | ALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |