Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719316 | 0.94 | DPP4 (0.44) | DPP4L3MBTL1ALDH1A1NUDT5FAP | |
| SCHEMBL5719372 | 0.89 | DPP4 (0.38) | DPP4L3MBTL1ALDH1A1FAPHTR2A | |
| SCHEMBL5776035 | 0.88 | DPP4 (0.39) | DPP4L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL5718955 | 0.86 | DPP4 (0.38) | DPP4L3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL5776754 | 0.84 | DPP4 (0.39) | DPP4L3MBTL1ALDH1A1FAPADRB1 | |
| SCHEMBL5775989 | 0.81 | DPP4 (0.46) | DPP4L3MBTL1ALDH1A1NUDT5FAP | |
| Acetic Acid SCHEMBL5718916 | 0.81 | DPP4 (0.47) | DPP4L3MBTL1ALDH1A1NUDT5ADRB1 | |
| SCHEMBL5774800 | 0.81 | DPP4 (0.50) | DPP4L3MBTL1ALDH1A1NUDT5FAP | |
| Acetic Acid Methyl Ester SCHEMBL5719126 | 0.80 | DPP4 (0.46) | DPP4L3MBTL1ALDH1A1NUDT5FAP | |
| Trifluoroacetic Acid SCHEMBL5719504 | 0.79 | DPP4 (0.50) | DPP4L3MBTL1ALDH1A1NUDT5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | DPP4 1/4885L3MBTL1 4196/4885ALDH1A1 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.