Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719316 | 0.90 | DPP4 (0.44) | DPP4L3MBTL1FAPALDH1A1 | |
| SCHEMBL5771953 | 0.84 | DPP4 (0.44) | DPP4HTR2AL3MBTL1FAPALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5719549 | 0.84 | DPP4 (0.42) | DPP4HTR1AHTR2AL3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL5719051 | 0.82 | DPP4 (0.53) | DPP4HTR1AHTR2AL3MBTL1ALDH1A1 | |
| SCHEMBL5719372 | 0.82 | DPP4 (0.38) | DPP4HTR2AL3MBTL1FAPALDH1A1 | |
| SCHEMBL5718995 | 0.81 | DPP4 (0.44) | DPP4HTR1AHTR2AL3MBTL1LMNA | |
| Acetonitrile SCHEMBL5718839 | 0.80 | DPP4 (0.40) | DPP4HTR1AHTR2AL3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL5718914 | 0.80 | MEN1 (0.46) | DPP4HTR1AHTR2AL3MBTL1LMNA | |
| SCHEMBL5718813 | 0.80 | DPP4 (0.52) | DPP4HTR1AHTR2AL3MBTL1LMNA | |
| SCHEMBL5789590 | 0.79 | DPP4 (0.59) | DPP4HTR1AHTR2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | DPP4 1/4885THRB 1295/4885HTR1A 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.