Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ATF1 | P18846 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431524 | 0.85 | STK17B (0.45) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL5436631 | 0.78 | NUDT1 (0.43) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL5787248 | 0.77 | MAPK8 (0.43) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL5786509 | 0.76 | NUDT1 (0.45) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL5431534 | 0.76 | STK17B (0.37) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| Hydrochloric Acid SCHEMBL5788283 | 0.75 | NUDT1 (0.44) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL22261132 | 0.73 | MAPK8 (0.54) | NUDT1MAPK8JAK2JAK1JAK3 | |
| SCHEMBL1938007 | 0.73 | STK17A (0.50) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL23627324 | 0.72 | MAPK8 (0.40) | STK17BSTK17ANUDT1MAPK8JAK2 | |
| SCHEMBL5789412 | 0.71 | NUDT1 (0.42) | STK17BSTK17ANUDT1MAPK8JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724264-A1 | NITRILES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-11-22 | — | — | EP | disclosed |