Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 18/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535678 | 0.91 | CCR2 (0.41) | TACR1CCR2KCNH2 | |
| SCHEMBL3534554 | 0.89 | CCR2 (0.39) | TACR1CCR2KCNH2 | |
| SCHEMBL3528790 | 0.87 | TACR1 (0.43) | TACR1CCR2 | |
| SCHEMBL2480202 | 0.83 | CCR2 (0.42) | TACR1CCR2KCNH2P2RX1 | |
| SCHEMBL2989300 | 0.83 | CCR2 (0.40) | TACR1CCR2 | |
| SCHEMBL3532857 | 0.83 | CCR2 (0.42) | TACR1CCR2KCNH2 | |
| SCHEMBL5635509 | 0.82 | CCR2 (0.39) | TACR1CCR2 | |
| SCHEMBL4768560 | 0.81 | CETP (0.37) | TACR1CCR2KCNH2 | |
| SCHEMBL13255065 | 0.81 | CETP (0.52) | — | |
| SCHEMBL2479621 | 0.80 | CCR2 (0.37) | TACR1CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670768-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037796-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |