SCHEMBL5772639

SCHEMBL5772639

C=C[Si](C)(C)c1cccc([Si](C)(C)C=C)c1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17973720 0.87 TP53 (0.47) NR1H2NR1H3TP53TDP1
SCHEMBL10621571 0.85 TP53 (0.50) NR1H2NR1H3TP53TDP1
SCHEMBL20972931 0.84 NR1H2 (0.43) NR1H2NR1H3
SCHEMBL453982 0.82 NR1H2 (0.48) NR1H2NR1H3
SCHEMBL824795 0.82 TSHR (0.37) NR1H2NR1H3
SCHEMBL7628213 0.82 BRD4 (0.44) NR1H2NR1H3TP53TDP1
SCHEMBL18234156 0.80 NR1H2 (0.49) NR1H2NR1H3
SCHEMBL18868022 0.80 NR1H2 (0.38) NR1H2NR1H3
SCHEMBL7628210 0.80 NR1H2 (0.34) NR1H2NR1H3
SCHEMBL5773688 0.80 TP53 (0.33) NR1H2NR1H3TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9403925-B2 Curable composition and cured article ADEKA CORPORATION (JP) 2016-08-02 US claimed
EP-2772505-B1 PHOTOCURABLE RESIN COMPOSITION AND NOVEL SILOXANE COMPOUND ADEKA CORP (JP) 2017-11-15 EP disclosed
US-9403925-B2 Curable composition and cured article ADEKA CORPORATION (JP) 2016-08-02 US disclosed
US-9063415-B2 Photocurable resin composition and novel siloxane compound ADEKA CORPORATION (JP) 2015-06-23 US disclosed
EP-2599836-B1 CURABLE COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION ADEKA CORP (JP) 2015-03-25 EP disclosed
EP-2772505-A1 PHOTOCURABLE RESIN COMPOSITION AND NOVEL SILOXANE COMPOUND Adeka Corporation (JP) 2014-09-03 EP disclosed
US-20140205949-A1 PHOTOCURABLE RESIN COMPOSITION AND NOVEL SILOXANE COMPOUND ADEKA CORPORATION (JP) 2014-07-24 US disclosed
US-20140187715-A1 CURABLE COMPOSITION AND CURED ARTICLE ADEKA CORPORATION (JP) 2014-07-03 US disclosed
EP-2749581-A1 CURABLE COMPOSITION AND CURED ARTICLE Adeka Corporation (JP) 2014-07-02 EP disclosed
US-8470937-B2 Curable composition for semiconductor encapsulation ADEKA CORPORATION (JP) 2013-06-25 US disclosed
EP-2599836-A1 CURABLE COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION Adeka Corporation (JP) 2013-06-05 EP disclosed
US-20120126435-A1 CURABLE COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION ADEKA CORPORATION (JP) 2012-05-24 US disclosed
US-20060134336-A1 Novel polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR CORPORATION (JP) 2006-06-22 US disclosed
EP-1661934-A1 Polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR Corporation (JP) 2006-05-31 EP disclosed
EP-0661331-B1 Silicon-containing polymer, process for preparing the same and monomer thereof KANEGAFUCHI CHEMICAL IND (JP) 2001-05-23 EP disclosed
EP-0661332-B1 Silicon-containing reactive polymer and curable resin composition comprising the same KANEGAFUCHI CHEMICAL IND (JP) 2000-04-12 EP disclosed
US-5691433-A POLYCARBOSILANES; HEAT RESISTANCE, SOLUBILITY KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-11-25 US disclosed
EP-0661331-A2 Silicon-containing polymer, process for preparing the same and monomer thereof Kanegafuchi Chemical Industry Co., Ltd. (JP) 1995-07-05 EP disclosed
EP-0661332-A2 Silicon-containing reactive polymer and curable resin composition comprising the same Kanegafuchi Chemical Industry Co., Ltd. (JP) 1995-07-05 EP disclosed