SCHEMBL18868022

SCHEMBL18868022

C=C[Si](C)(C)c1cccc(NF)c1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824795 0.84 TSHR (0.37) NR1H2NR1H3TGM2
SCHEMBL5772639 0.80 NR1H2 (0.42) NR1H2NR1H3
SCHEMBL6765203 0.79 TGM2 (0.42) NR1H2NR1H3TGM2
SCHEMBL17973720 0.73 TP53 (0.47) NR1H2NR1H3
SCHEMBL26796875 0.73 F2R (0.48) NR1H2NR1H3
SCHEMBL12438755 0.73 NR1H2 (0.35) NR1H2NR1H3
SCHEMBL26797067 0.73 NR1H2 (0.38) NR1H2NR1H3TGM2
SCHEMBL10621571 0.72 TP53 (0.50) NR1H2NR1H3
SCHEMBL15942920 0.72 NR1H2 (0.37) NR1H2NR1H3TGM2
SCHEMBL14942616 0.72 NR1H2 (0.37) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9840601-B2 Method for producing a cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-12 US disclosed
US-20170137583-A1 METHOD FOR PRODUCING A CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-18 US disclosed