Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762162 | 0.87 | IDO1 (0.46) | IDO1TDO2DPP4ALDH1A1MAPK1 | |
| SCHEMBL11080503 | 0.87 | IDO1 (0.46) | IDO1TDO2ALDH1A1MAPK1MAOA | |
| SCHEMBL2401036 | 0.87 | IDO1 (0.46) | IDO1TDO2DPP4ALDH1A1MAPK1 | |
| SCHEMBL29278100 | 0.87 | IDO1 (0.46) | IDO1TDO2DPP4ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL17764461 | 0.85 | IDO1 (0.49) | IDO1TDO2ALDH1A1MAPK1MAOA | |
| Hydrochloric Acid SCHEMBL30762179 | 0.85 | IDO1 (0.49) | IDO1TDO2ALDH1A1MAPK1MAOA | |
| SCHEMBL27655405 | 0.83 | IDO1 (0.50) | IDO1TDO2ALDH1A1MAPK1MAOA | |
| SCHEMBL5302829 | 0.82 | IDO1 (0.50) | IDO1TDO2DPP4ALDH1A1MAPK1 | |
| SCHEMBL14014456 | 0.81 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPK1MAOA | |
| SCHEMBL749481 | 0.81 | IDO1 (0.48) | IDO1TDO2ALDH1A1MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676635-A2 | Immobilisable ligands derived from ethylenediamine | Johnson Matthey PLC (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20060135355-A1 | Nitrogen-containing ligands | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-06-22 | — | — | US | disclosed |
| EP-1545772-A2 | NITROGEN-CONTAINING LIGANDS | Johnson Matthey PLC (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014551-A2 | IMMOBILISED LIGANDS DERIVED FROM ETHYLENEDIAMINE | JOHNSON MATTHEY PLC (GB) | 2004-02-19 | — | — | WO | disclosed |