Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779245 | 0.95 | MAPT (0.43) | TDP1RIOK2MAPTTRPV1KDM4E | |
| SCHEMBL5775624 | 0.95 | MAPT (0.43) | TDP1RIOK2MAPTTRPV1KDM4E | |
| SCHEMBL5914010 | 0.95 | MAPT (0.43) | TDP1RIOK2MAPTTRPV1KDM4E | |
| SCHEMBL5770617 | 0.92 | RIOK2 (0.38) | RIOK2NR3C2MAPTALDH1A1NPSR1 | |
| SCHEMBL5775894 | 0.86 | RIOK2 (0.48) | CYP1A2RIOK2NR3C2MAPTNPSR1 | |
| SCHEMBL5776450 | 0.84 | MAPK10 (0.40) | LMNAMMERIOK2NR3C2MAPT | |
| SCHEMBL5770717 | 0.81 | RIOK2 (0.44) | LMNAMMERIOK2NR3C2MAPT | |
| SCHEMBL5774799 | 0.79 | MAPK10 (0.38) | RIOK2MAPTTRPV1KDM4E | |
| SCHEMBL5775211 | 0.79 | MAPK10 (0.38) | RIOK2MAPTTRPV1KDM4E | |
| SCHEMBL5769845 | 0.79 | MAPK10 (0.38) | RIOK2MAPTTRPV1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |