Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914010 | 1.00 | MAPT (0.43) | MAPTKDM4ETRPV1TLR7RORA | |
| SCHEMBL5775624 | 1.00 | MAPT (0.43) | MAPTKDM4ETRPV1TLR7RORA | |
| SCHEMBL5772772 | 0.95 | LMNA (0.38) | MAPTKDM4ETRPV1RIOK2TDP1 | |
| SCHEMBL5770617 | 0.90 | RIOK2 (0.38) | MAPTKDM4ERIOK2 | |
| SCHEMBL5774799 | 0.84 | MAPK10 (0.38) | MAPTKDM4ETRPV1RIOK2 | |
| SCHEMBL5769845 | 0.84 | MAPK10 (0.38) | MAPTKDM4ETRPV1RIOK2 | |
| SCHEMBL5775211 | 0.84 | MAPK10 (0.38) | MAPTKDM4ETRPV1RIOK2 | |
| SCHEMBL5775894 | 0.84 | RIOK2 (0.48) | MAPTKDM4ERIOK2L3MBTL1 | |
| SCHEMBL5750867 | 0.84 | TRPV1 (0.41) | MAPTKDM4ETRPV1RORARORC | |
| SCHEMBL5773999 | 0.81 | RIOK2 (0.42) | MAPTKDM4ETRPV1RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |