Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907912 | 0.85 | ALDH1A1 (0.64) | HRH3KDM4EALDH1A1 | |
| SCHEMBL5772279 | 0.81 | HRH3 (0.70) | HRH3 | |
| SCHEMBL5767930 | 0.77 | HRH3 (0.77) | HRH3 | |
| SCHEMBL3898840 | 0.76 | HRH3 (0.76) | HRH3 | |
| SCHEMBL3897106 | 0.76 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3901865 | 0.76 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3896019 | 0.76 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3900704 | 0.74 | HRH3 (0.97) | HRH3 | |
| SCHEMBL3896005 | 0.74 | HRH3 (0.81) | HRH3 | |
| SCHEMBL3903480 | 0.74 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451167-B1 | PHENYLALKYNES | ORTHO MCNEIL PHARM INC (US) | 2006-03-08 | — | — | EP | claimed |