Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HCN1 | O60741 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877679 | 0.79 | SOAT1 (0.46) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4877681 | 0.79 | SOAT1 (0.46) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4872820 | 0.78 | SOAT1 (0.47) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4872809 | 0.78 | SOAT1 (0.47) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5772979 | 0.77 | SOAT1 (0.46) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5772984 | 0.77 | SOAT1 (0.46) | SOAT1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4878711 | 0.77 | SOAT1 (0.45) | SOAT1KMT2AALDH1A1TACR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4878702 | 0.77 | SOAT1 (0.45) | SOAT1KMT2AALDH1A1TACR1SLC6A4 | |
| SCHEMBL5475853 | 0.71 | KMT2A (0.75) | KMT2AALDH1A1SLC6A4 | |
| SCHEMBL5475847 | 0.71 | KMT2A (0.75) | KMT2AALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |