Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877681 | 1.00 | SOAT1 (0.46) | SOAT1KMT2ASLC6A4TACR1MTNR1A | |
| SCHEMBL4878278 | 0.92 | SOAT1 (0.48) | SOAT1KMT2ASLC6A4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4878702 | 0.90 | SOAT1 (0.45) | SOAT1KMT2ASLC6A4TACR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4878711 | 0.90 | SOAT1 (0.45) | SOAT1KMT2ASLC6A4TACR1SIGMAR1 | |
| SCHEMBL5771434 | 0.89 | HTR6 (0.41) | SOAT1KMT2AMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL5771439 | 0.89 | HTR6 (0.41) | SOAT1KMT2AMTNR1AMTNR1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4880495 | 0.88 | HTR6 (0.40) | SOAT1KMT2AMTNR1AMTNR1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4872697 | 0.88 | HTR6 (0.40) | SOAT1KMT2AMTNR1AMTNR1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4872712 | 0.88 | HTR6 (0.40) | SOAT1KMT2AMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL4872820 | 0.87 | SOAT1 (0.47) | SOAT1KMT2ASLC6A4TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | SOAT1 502/4885KMT2A 1132/4885SLC6A4 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.