Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5775150 | 0.98 | SSTR3 (0.30) | SSTR3 | |
| SCHEMBL5776282 | 0.88 | HPGDS (0.38) | SSTR3HPGDSBRAFMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5775499 | 0.84 | HPGDS (0.32) | SSTR3HPGDSMEN1KMT2A | |
| SCHEMBL5772317 | 0.83 | HPGDS (0.32) | SSTR3HPGDSMEN1KMT2A | |
| SCHEMBL5771799 | 0.82 | SSTR3 (0.32) | SSTR3HPGDSMEN1KMT2A | |
| SCHEMBL5772122 | 0.82 | HPGDS (0.31) | HPGDSMEN1KMT2A | |
| SCHEMBL5775213 | 0.82 | TTK (0.31) | HPGDSMEN1KMT2A | |
| SCHEMBL5773000 | 0.81 | HPGDS (0.33) | SSTR3HPGDSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5772618 | 0.81 | SSTR3 (0.31) | SSTR3 | |
| Hydrochloric Acid SCHEMBL5775314 | 0.81 | TTK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | claimed |