SCHEMBL5773276

SCHEMBL5773276

CC(=O)C(S)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746954 1.00
SCHEMBL31494789 1.00
SCHEMBL6514589 0.73
SCHEMBL4620545 0.73
SCHEMBL906464 0.71
SCHEMBL6155982 0.69
SCHEMBL8034630 0.69
SCHEMBL16248435 0.67
SCHEMBL17486920 0.67
SCHEMBL19275819 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684175-A Preparation method of ethyl thioglycolate 长沙贝塔医药科技有限公司 2025-03-25 CN claimed
CN-119684175-B Preparation method of ethyl thioglycolate 长沙贝塔医药科技有限公司 2026-03-17 CN disclosed
CN-119684175-A Preparation method of ethyl thioglycolate 长沙贝塔医药科技有限公司 2025-03-25 CN disclosed
CN-119684175-A Preparation method of ethyl thioglycolate 长沙贝塔医药科技有限公司 2025-03-25 CN disclosed
EP-1054887-B1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS AMGEN INC (US) 2006-04-12 EP disclosed
US-6583154-B1 Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines AMGEN INC. 2003-06-24 US disclosed
US-6187777-B1 PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS AMGEN INC. 2001-02-13 US disclosed
EP-1054887-A1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS Amgen Inc. (US) 2000-11-29 EP disclosed
WO-1999040091-A1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS AMGEN INC. (US) 1999-08-12 WO disclosed
EP-0298543-B1 THIAPENTANAMIDE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-09-29 EP disclosed
US-5153330-A Thiapentanamide derivatives SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) 1992-10-06 US disclosed
EP-0298543-A2 Thiapentanamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-01-11 EP disclosed