⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620545 | 1.00 | — | — | |
| SCHEMBL31494789 | 0.73 | — | — | |
| SCHEMBL5773276 | 0.73 | — | — | |
| SCHEMBL2746954 | 0.73 | — | — | |
| SCHEMBL4361943 | 0.69 | — | — | |
| SCHEMBL5071821 | 0.68 | — | — | |
| SCHEMBL6671350 | 0.67 | — | — | |
| SCHEMBL25487800 | 0.65 | — | — | |
| SCHEMBL641605 | 0.65 | — | — | |
| SCHEMBL3055970 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045555-B2 | Vaccine against amyloid folding intermediate | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2015-06-02 | — | — | US | claimed |
| US-20050025740-A1 | Polyoxime compounds and their preparation | AMYLIN PHARMACEUTICALS, INC. | 2005-02-03 | — | — | US | disclosed |
| US-6663869-B1 | Linkages between polypeptide organic molecules are oxime linkages formed by reaction of a keto, aldehyde or amino-oxy group on the amino acid | GRYPHON THERAPEUTICS, INC. | 2003-12-16 | — | — | US | disclosed |
| US-20030187221-A1 | Peptides for the preparation of vaccines against bordetella pertussis and bordetella parapertussis | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN VOLKSGEZONDHEID EN CULTUUR (NL) | 2003-10-02 | — | — | US | disclosed |
| EP-1294890-A2 | PEPTIDES FOR THE PREPARATION OF VACCINES AGAINST BORDETELLA PERTUSSIS AND BORDETELLA PARAPERTUSSIS | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 2003-03-26 | — | — | EP | disclosed |
| EP-0850244-B1 | TOXOPLASMA GONDII GLYCOCONJUGATES | ORGANON TEKNIKA BV (NL) | 2002-07-31 | — | — | EP | disclosed |
| US-20020058288-A1 | Compound for use in the detection and prevention of parasitic infection of humans | AKZO NOBEL N.V. (NL) | 2002-05-16 | — | — | US | disclosed |
| EP-1174505-A1 | (Poly)peptides for the preparation of vaccines against Bordetella pertussis and/or Bordetella parapertussis, vaccines based upon such (poly)peptides, and antibodies against such peptides | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 2002-01-23 | — | — | EP | disclosed |
| WO-2002000695-A2 | PEPTIDES FOR THE PREPARATION OF VACCINES AGAINST BORDETELLA PERTUSSIS AND BORDETELLA PARAPERTUSSIS | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 2002-01-03 | — | — | WO | disclosed |
| US-6217873-B1 | HOMOGENEOUS; MEDICAL DIAGNOSIS | GRYPHON SCIENCES | 2001-04-17 | — | — | US | disclosed |
| WO-1997010249-A1 | TOXOPLASMA GONDII GLYCOCONJUGATES | AKZO NOBEL N.V. (NL) | 1997-03-20 | — | — | WO | disclosed |
| EP-0697891-A1 | POLYOXIME COMPOUNDS AND THEIR PREPARATION | Rose, Keith (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5444150-A | For use in solid phase peptide synthesis for introducing side chain bromoacetyl group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995018781-A1 | METHODS FOR SYNTHESIZING OLIGOMERS CONTAINING HYDROXY ACID UNITS | METABOLIX, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| WO-1994025071-A1 | POLYOXIME COMPOUNDS AND THEIR PREPARATION | ROSE KEITH (CH) | 1994-11-10 | — | — | WO | disclosed |
| EP-0590038-A4 | AMINO ACID DERIVATIVE AND BROMOACETYL MODIFIED PEPTIDES | US HEALTH (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0590038-A1 | AMINO ACID DERIVATIVE AND BROMOACETYL MODIFIED PEPTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5286846-A | Trifunctional reagents for solid phase synthesis | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPT. OF HEALTH AND HUMAN SERVICES (US) | 1994-02-15 | — | — | US | disclosed |
| WO-1992022318-A1 | AMINO ACID DERIVATIVE AND BROMOACETYL MODIFIED PEPTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the DEPARTEMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-23 | — | — | WO | disclosed |
| US-4613587-A | 2-MERCAPTOACETYL-PHENYLALANINE-LEUCINE AS ENZYME INHIBITOR, GENTAMICIN ANTIBIOTIC | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1986-09-23 | — | — | US | disclosed |