Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4343043 | 0.92 | TLR7 (0.40) | TLR7 | |
| SCHEMBL5750376 | 0.90 | GAA (0.41) | TLR7 | |
| SCHEMBL5750020 | 0.89 | TLR7 (0.48) | TLR7 | |
| SCHEMBL5746090 | 0.87 | TLR7 (0.48) | TLR7 | |
| SCHEMBL3865322 | 0.87 | TLR7 (0.48) | TLR7 | |
| SCHEMBL5122488 | 0.85 | TLR7 (0.41) | TLR7 | |
| SCHEMBL5800432 | 0.84 | TLR7 (0.60) | TLR7 | |
| SCHEMBL5751136 | 0.84 | TLR7 (0.42) | TLR7 | |
| SCHEMBL5353603 | 0.83 | TLR7 (0.59) | TLR7 | |
| SCHEMBL5748740 | 0.83 | TLR7 (0.42) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198232-B1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-23 | — | — | EP | claimed |
| US-6780873-B2 | FOR INDUCING CYTOKINE BIOSYNTHESIS IN ANIMALS, AND IN THE TREATMENT OF DISEASES, INCLUDING VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-24 | — | — | US | claimed |
| US-20040014754-A1 | Urea substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-22 | — | — | US | claimed |
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060009482-A1 | Screening method for identifying compounds that selectively induce interferon alpha | 3M INNOVATIVE PROPERTIES COMPANY | 2006-01-12 | — | — | US | disclosed |
| US-20020110840-A1 | Screening method for identifying compounds that selectively induce interferon alpha | 3M INNOVATIVE PROPERTIES COMPANY | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014754-A1 | Urea substituted imidazoquinolines | IFNG, EIF2AK2, IRF3 | TLR7 35/4885FAAH 2669/4885 |
| US-20060009482-A1 | Screening method for identifying compounds that selectively induce interferon alpha | IFNG, EIF2AK2, IFNAR1 | TLR7 120/4885FAAH 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.