Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29250309 | 0.88 | USP2 (0.42) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL4063731 | 0.79 | USP2 (0.32) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL1615448 | 0.79 | USP2 (0.32) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL3354765 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL27771573 | 0.78 | BCHE (0.39) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL29029079 | 0.78 | USP2 (0.36) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| SCHEMBL5858067 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2BCHECHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL3197279 | 0.78 | USP2 (0.31) | USP2SMN1; SMN2BCHE | |
| SCHEMBL21219152 | 0.78 | BCHE (0.33) | USP2SMN1; SMN2BCHEESR2 | |
| SCHEMBL27613482 | 0.77 | NR1H2 (0.33) | USP2SMN1; SMN2BCHENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574834-A | Fused tetracyclic compounds, compositions and uses thereof | 泰博生物科技股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118201929-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 广东弘烨医药科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |
| CN-113105475-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-110177551-A | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V生物科学股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-105939998-B | Heteroaryl compound and application thereof as BTK inhibitor | 默克专利有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105001225-B | The heterocyclic modulators of lipid synthesis | 3-V 生物科学公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-103237800-A | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2013-08-07 | — | — | CN | disclosed |
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | disclosed |
| EP-1670768-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037796-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| CN-1072222-C | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | UPJOHN CO (US) | 2001-10-03 | — | — | CN | disclosed |
| CN-1197457-A | Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring | UPJOHN CO (US) | 1998-10-28 | — | — | CN | disclosed |