Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868546 | 0.77 | NR1H2 (0.36) | NR1H2BCHE | |
| SCHEMBL5773612 | 0.77 | USP2 (0.38) | NR1H2BCHEUSP2SMN1; SMN2 | |
| SCHEMBL29250309 | 0.74 | USP2 (0.42) | NR1H2BCHEUSP2SMN1; SMN2 | |
| SCHEMBL3398897 | 0.72 | GPR119 (0.30) | — | |
| SCHEMBL28026573 | 0.71 | BCHE (0.35) | BCHEUSP2SMN1; SMN2 | |
| SCHEMBL4439029 | 0.71 | NR1H2 (0.42) | NR1H2BCHEUSP2SMN1; SMN2 | |
| SCHEMBL21219152 | 0.69 | BCHE (0.33) | BCHEUSP2SMN1; SMN2 | |
| SCHEMBL31460174 | 0.68 | BCHE (0.33) | NR1H2BCHEUSP2SMN1; SMN2 | |
| SCHEMBL15390474 | 0.68 | NR1H2 (0.39) | NR1H2BCHEUSP2SMN1; SMN2 | |
| SCHEMBL3110325 | 0.68 | NFKB1 (0.36) | NR1H2BCHEUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678586-A | Substituted quinoline CCR5 receptor antagonists | SCHERING AG (DE) | 2005-10-05 | — | — | CN | disclosed |