Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770807 | 0.89 | MAPT (0.46) | MAPTALDH1A1HSD17B10KDM4ERECQL | |
| SCHEMBL5773555 | 0.83 | KDM4E (0.32) | MAPTALDH1A1KDM4EPOLBESR2 | |
| SCHEMBL26244639 | 0.75 | MAPT (0.44) | MAPTALDH1A1HSD17B10KDM4ERECQL | |
| SCHEMBL10958465 | 0.75 | MAPT (0.46) | MAPTALDH1A1HSD17B10KDM4ERECQL | |
| SCHEMBL5768754 | 0.73 | SERPINE1 (0.38) | MAPTALDH1A1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL5771570 | 0.73 | LMNA (0.47) | MAPTALDH1A1HSD17B10KDM4ERECQL | |
| SCHEMBL5772064 | 0.73 | PIM1 (0.46) | KDM4EKMT2ALMNA | |
| SCHEMBL16048091 | 0.72 | CA12 (0.41) | MAPTALDH1A1KDM4EESR2L3MBTL1 | |
| SCHEMBL5768892 | 0.70 | PDE7B (0.41) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL21230547 | 0.70 | MAPT (0.56) | MAPTALDH1A1HSD17B10KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005027900-A1 | BENZOFURAN DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |