Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.69 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5772326 | 0.98 | NPY5R (0.67) | NPY5RPRKCIKDM4ESMN1; SMN2CNR2 | |
| SCHEMBL5773316 | 0.82 | NPY5R (1.00) | NPY5RPRKCIKDM4ESMN1; SMN2CNR2 | |
| Hydrochloric Acid SCHEMBL5774363 | 0.81 | NPY5R (0.97) | NPY5RPRKCIKDM4ESMN1; SMN2CNR2 | |
| SCHEMBL5776579 | 0.79 | NPY5R (0.72) | NPY5RPRKCIKDM4ESMN1; SMN2CNR2 | |
| Hydrochloric Acid SCHEMBL5771345 | 0.77 | NPY5R (0.69) | NPY5RPRKCIKDM4ESMN1; SMN2CNR2 | |
| SCHEMBL22727925 | 0.71 | NPY5R (0.65) | NPY5RPRKCIKDM4EALDH1A1LMNA | |
| SCHEMBL5423216 | 0.71 | KDM4E (0.51) | NPY5RKDM4ESMN1; SMN2CNR2ALDH1A1 | |
| SCHEMBL5771155 | 0.71 | NPY5R (0.78) | NPY5RPRKCIKDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5773169 | 0.69 | NPY5R (0.74) | NPY5RPRKCISMN1; SMN2MEN1KMT2A | |
| SCHEMBL16453796 | 0.67 | HRH4 (0.62) | NPY5RKDM4ESMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |