Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597632 | 0.81 | PTGER4 (0.41) | NR1H2NR1H3 | |
| SCHEMBL27581313 | 0.80 | KDM4E (0.35) | NR1H2NR1H3 | |
| SCHEMBL7103580 | 0.80 | — | — | |
| SCHEMBL27597664 | 0.76 | PTGER4 (0.36) | — | |
| SCHEMBL27579815 | 0.76 | TLR7 (0.34) | NR1H2NR1H3 | |
| SCHEMBL6427478 | 0.74 | PTGER4 (0.37) | — | |
| SCHEMBL27618333 | 0.73 | — | — | |
| SCHEMBL8139492 | 0.72 | BACE1 (0.35) | NR1H2NR1H3 | |
| SCHEMBL27597647 | 0.65 | GPR4 (0.41) | — | |
| SCHEMBL27695518 | 0.64 | PTGER4 (0.46) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-B1 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMA (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1499305-A2 | USE OF EP4 RECEPTOR LIGANDS IN THE TREATMENT OF IL-6 INVOLVED DISEASES | Pfizer Japan Inc. (JP) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003086371-A2 | USE OF EP4 RECEPTOR LIGANDS IN THE TREATMENT OF IL-6 INVOLVED DISEASES | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |