Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5776956 | 0.99 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL5776561 | 0.87 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL5772664 | 0.86 | MEN1 (0.31) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5775252 | 0.85 | MEN1 (0.30) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5807142 | 0.85 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL5776818 | 0.85 | USP30 (0.35) | MEN1KMT2A | |
| SCHEMBL5771501 | 0.84 | LMNA (0.30) | — | |
| Hydrochloric Acid SCHEMBL5773710 | 0.84 | USP30 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7183216 | 0.83 | — | — | |
| SCHEMBL5771084 | 0.83 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | claimed |