Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774517 | 0.85 | KCNH2 (0.34) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL4274200 | 0.82 | KCNH2 (0.72) | KCNH2SLC2A1 | |
| SCHEMBL7502188 | 0.79 | SLC2A1 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL7499192 | 0.79 | SLC2A1 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL6987928 | 0.79 | SLC2A1 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL6979457 | 0.77 | SLC2A1 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL6987295 | 0.76 | CYP2D6 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL6981059 | 0.76 | SLC2A1 (0.42) | KCNH2SLC2A1 | |
| SCHEMBL6979541 | 0.76 | KCNH2 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL7510786 | 0.73 | SLC2A1 (0.47) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |