Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774506 | 0.85 | KCNH2 (0.49) | KCNH2MCHR1SLC2A1 | |
| SCHEMBL5775045 | 0.82 | KCNH2 (0.52) | KCNH2SLC2A1PRMT5WDR77DRD2 | |
| SCHEMBL4274200 | 0.67 | KCNH2 (0.72) | KCNH2SLC2A1 | |
| SCHEMBL5775396 | 0.66 | KCNH2 (0.49) | KCNH2HTR1ASLC2A1DRD2DRD3 | |
| SCHEMBL5258710 | 0.66 | KCNH2 (0.45) | KCNH2HTR1ASLC2A1PRMT5WDR77 | |
| SCHEMBL5255397 | 0.65 | KCNH2 (0.46) | KCNH2SLC2A1PRMT5WDR77 | |
| SCHEMBL6987928 | 0.65 | SLC2A1 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL31041482 | 0.65 | HRH3 (0.45) | — | |
| SCHEMBL5253700 | 0.64 | KCNH2 (0.49) | KCNH2HTR1ASLC2A1 | |
| SCHEMBL7502188 | 0.64 | SLC2A1 (0.48) | KCNH2HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |