Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776735 | 0.99 | HSP90AA1 (0.43) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL5777155 | 0.83 | HSP90AA1 (0.39) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL5777572 | 0.83 | HSP90AA1 (0.41) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL30405316 | 0.82 | HSP90AA1 (0.42) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL28907586 | 0.82 | HSP90AA1 (0.42) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL5776309 | 0.79 | HSP90AA1 (0.44) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL28745179 | 0.78 | HTR2C (0.54) | PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL6282952 | 0.75 | HSP90AA1 (0.40) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL6730319 | 0.75 | PDGFRB (0.36) | HSP90AA1HSP90B1PDGFRBHSP90AB1ENPP2 | |
| SCHEMBL23501691 | 0.74 | HSP90AB1 (0.59) | PDGFRBHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483257-B1 | QUINAZOLINE COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2006-09-13 | — | — | EP | disclosed |