Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777572 | 0.77 | HSP90AA1 (0.41) | PDGFRBENPP2FYNHSP90AA1HSP90B1 | |
| SCHEMBL30405316 | 0.76 | HSP90AA1 (0.42) | PDGFRBENPP2FYNHSP90AA1HSP90B1 | |
| SCHEMBL28907586 | 0.76 | HSP90AA1 (0.42) | PDGFRBENPP2FYNHSP90AA1HSP90B1 | |
| SCHEMBL5776735 | 0.76 | HSP90AA1 (0.43) | PDGFRBENPP2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL5774769 | 0.75 | HSP90AA1 (0.43) | PDGFRBENPP2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL5776309 | 0.73 | HSP90AA1 (0.44) | PDGFRBENPP2HSP90AA1HSP90B1HSP90AB1 | |
| SCHEMBL28518413 | 0.73 | MAPT (0.43) | PDGFRBHSP90AA1HSP90AB1MAPT | |
| SCHEMBL28564871 | 0.73 | MAPT (0.43) | PDGFRBHSP90AA1HSP90AB1MAPT | |
| SCHEMBL28745179 | 0.72 | HTR2C (0.54) | PDGFRBENPP2HSP90AB1KDR | |
| SCHEMBL5777155 | 0.71 | HSP90AA1 (0.39) | PDGFRBENPP2FYNHSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029859-A1 | Compounds useful in therapy | PFIZER INC. | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029859-A1 | Compounds useful in therapy | ADRA1D, HSD3B1, PTGER1 | PDGFRB 2626/4885ENPP2 579/4885FYN 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.