Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776597 | 0.84 | HTR2C (0.32) | HTR2C | |
| SCHEMBL4502692 | 0.81 | HTR2C (0.54) | HTR2CALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL5774361 | 0.81 | CDK4 (0.32) | HTR2CCDK4CCND1CCNE1CDK2 | |
| SCHEMBL5323120 | 0.76 | TP53 (0.33) | HTR2CALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL5771717 | 0.74 | MEN1 (0.33) | KMT2A | |
| SCHEMBL3258832 | 0.70 | CRHR1 (0.35) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL5291917 | 0.70 | CNR1 (0.37) | — | |
| SCHEMBL3257816 | 0.70 | KDM4E (0.36) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL4490087 | 0.68 | HTR2C (0.47) | HTR2CALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL4506359 | 0.68 | HTR2C (0.47) | HTR2CALDH1A1HPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718652-A2 | PYRAZOLOPYRIMIDINES FOR COMBATTING UNWANTED MICROORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082907-A2 | PYRAZOLOPYRIMIDINES FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2005-09-09 | — | — | WO | disclosed |