Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.67 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18461518 | 0.82 | HTR1B (0.72) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL375979 | 0.81 | HTR1B (1.00) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL8382821 | 0.81 | HTR1B (0.71) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL5746097 | 0.80 | HTR1B (0.97) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL8469545 | 0.80 | HTR1B (0.97) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL5750446 | 0.78 | HTR1B (0.67) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL5748111 | 0.78 | HTR1B (0.67) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL5745878 | 0.78 | HTR1B (0.67) | HTR1BHTR2BGPR65FEN1 | |
| Hydrochloric Acid SCHEMBL5750394 | 0.76 | HTR1B (0.68) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| SCHEMBL5748949 | 0.76 | HTR1B (0.64) | HTR1BHTR2BGPR65ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901474-B1 | ARYL PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-04-19 | — | — | EP | disclosed |