Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5777672 | 0.98 | NPY5R (0.49) | NPY5RMAOAMAOBSOS1PTGER1 | |
| SCHEMBL5774636 | 0.74 | MAPKAPK2 (0.39) | PTGER1SIGMAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL5773747 | 0.73 | NPY5R (0.51) | NPY5RSOS1HTR2CMEN1KMT2A | |
| SCHEMBL5775024 | 0.72 | NPY5R (0.53) | NPY5RMAOBSOS1SLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5774370 | 0.72 | NPY5R (0.50) | NPY5RSOS1HTR2CGABRA1MEN1 | |
| Hydrochloric Acid SCHEMBL5771749 | 0.68 | NPY5R (0.73) | NPY5RMAOAMAOBMEN1KMT2A | |
| SCHEMBL7700269 | 0.64 | PDE10A (0.50) | MAOBBCHEACHESLC18A3SIGMAR1 | |
| SCHEMBL187977 | 0.64 | GABRA1 (0.44) | BCHEACHESLC18A3SIGMAR1HTR2C | |
| SCHEMBL5775959 | 0.64 | NPY5R (0.48) | NPY5RMAOAMAOBPTGER1MEN1 | |
| SCHEMBL8166215 | 0.64 | NPC1 (0.52) | SLC18A3SIGMAR1GABRA1KMT2AGABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |