Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777403 | 0.83 | ALB (0.75) | ALBKMT2AMEN1RAB9AHDAC1 | |
| SCHEMBL9262889 | 0.83 | ALB (1.00) | ALBLMNAKMT2ASMN1; SMN2PTGER4 | |
| SCHEMBL9262876 | 0.83 | ALB (1.00) | ALBLMNAKMT2ASMN1; SMN2PTGER4 | |
| SCHEMBL5777537 | 0.82 | ALB (0.47) | ALBLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9261385 | 0.79 | ALB (0.75) | ALBLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5780463 | 0.79 | ALB (0.81) | ALBLMNAKMT2ASMN1; SMN2PTGER4 | |
| SCHEMBL9261371 | 0.79 | ALB (0.75) | ALBLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9265413 | 0.79 | ALB (0.74) | ALBLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9265401 | 0.79 | ALB (0.74) | ALBLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5780243 | 0.75 | ALB (0.41) | ALBKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |