Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.75 |
| ▸ | RIOK2 | Q9BVS4 | 7/20 | 0.37 |
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.37 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262876 | 0.86 | ALB (1.00) | ALBHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL9262889 | 0.86 | ALB (1.00) | ALBHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL5775741 | 0.83 | ALB (0.70) | ALBMAPK10MAPK8HDAC1HDAC6 | |
| SCHEMBL5780463 | 0.82 | ALB (0.81) | ALBGSK3AHDAC1HDAC6MEN1 | |
| SCHEMBL5908387 | 0.82 | ALB (0.50) | ALBRIOK2GSK3AMAPK10HDAC1 | |
| SCHEMBL9261371 | 0.79 | ALB (0.75) | ALBMEN1RAB9AKMT2A | |
| SCHEMBL9261385 | 0.79 | ALB (0.75) | ALBMEN1RAB9AKMT2A | |
| SCHEMBL9265401 | 0.78 | ALB (0.74) | ALBMEN1RAB9AKMT2A | |
| SCHEMBL9265413 | 0.78 | ALB (0.74) | ALBMEN1RAB9AKMT2A | |
| SCHEMBL9266539 | 0.76 | ALB (0.83) | ALBHDAC1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |