SCHEMBL5775892

SCHEMBL5775892

CC(C)(N)c1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21838537 0.98 MAPT (0.44)
Hydrochloric Acid SCHEMBL21838536 0.95 MAPT (0.43)
SCHEMBL29175499 0.85
SCHEMBL30514609 0.81 MAPT (0.41)
SCHEMBL9442571 0.81
SCHEMBL20734518 0.80
SCHEMBL4983413 0.79 MAPT (0.48)
SCHEMBL418090 0.79
SCHEMBL28297060 0.79 MAPT (0.48)
SCHEMBL181942 0.79 MAPT (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117160518-A Zeolite molecular sieve loaded platinum monoatomic cluster catalyst and its preparation method and use 南京工业大学 2023-12-05 CN disclosed
CN-116655476-A Preparation method of amino alcohol 北京大学 2023-08-29 CN disclosed
CN-116099537-A Ni-NiO multiphase magnetic catalyst, preparation method and application thereof 东南大学 2023-05-12 CN disclosed
CN-112939790-A Method for preparing tertiary amine organic compound by decomposing substituted formamide under mild condition 天津理工大学 2021-06-11 CN disclosed
CN-112174762-A Method for preparing tertiary amine organic compound by photocatalytic decomposition of substituted formamide 天津理工大学 2021-01-05 CN disclosed
CN-107987040-B Synthesis of 2-N-methylaminomethyl-5-N-methylaminomethylfuran 厦门大学 2020-05-29 CN disclosed
US-20060293297-A1 Cyanofluoropyrrolidine derviative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2006-12-28 US disclosed
EP-1627870-A1 CYANOFLUOROPYRROLIDINE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2006-02-22 EP disclosed
US-5760025-A ADMINISTERING TESTOSTERONE 5A-REDUCTASE INHIBITORS SANKYO COMPANY, LIMITED (JP) 1998-06-02 US disclosed
US-5717088-A REACTING WITH A CYANOPHOSPHATE IN THE PRESENCE OF AN ALKALI METAL CYANIDE SANKYO COMPANY, LIMITED (JP) 1998-02-10 US disclosed
US-5698720-A INTERMEDIATES FOR TESTOSTERONE 5-ALPHA-REDUCTASE INHIBITORS SANKYO COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0567271-B1 Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses SANKYO CO (JP) 1997-07-02 EP disclosed
EP-0725074-A2 Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives SANKYO COMPANY LIMITED (JP) 1996-08-07 EP disclosed
US-5536714-A Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses SANKYO COMPANY, LIMITED (JP) 1996-07-16 US disclosed
EP-0567271-A2 Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses SANKYO COMPANY LIMITED (JP) 1993-10-27 EP disclosed
US-RE29324-E N-Substituted aspartyl peptide amides G. D. SEARLE & CO. (US) 1977-07-26 US disclosed