Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778378 | 0.76 | NPY5R (0.62) | NPY5R | |
| SCHEMBL5772401 | 0.72 | NPY5R (0.70) | NPY5R | |
| SCHEMBL5776765 | 0.67 | NPY5R (0.51) | NPY5RMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5771479 | 0.66 | NPY5R (0.57) | NPY5RLMNAMEN1KMT2ACCNB2 | |
| SCHEMBL5775164 | 0.65 | NPY5R (0.58) | NPY5RCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL5773128 | 0.65 | NPY5R (0.60) | NPY5RCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL5774044 | 0.65 | NPY5R (0.60) | NPY5RCCNB2CDK1CCNB1CDK5 | |
| SCHEMBL7650453 | 0.64 | DHODH (0.55) | NPY5RKDM4ELMNAMEN1NPC1 | |
| SCHEMBL5773508 | 0.63 | NPY5R (0.62) | NPY5R | |
| SCHEMBL3985467 | 0.63 | ALDH1A1 (0.57) | NPY5RKDM4ELMNAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |