Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764847 | 0.87 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL5775582 | 0.86 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5777234 | 0.86 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL14573147 | 0.85 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5777425 | 0.83 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL5774252 | 0.80 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL5774180 | 0.76 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL14341199 | 0.74 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL5764668 | 0.73 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL5764517 | 0.73 | KCNH2 (0.58) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343780-B1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2006-09-20 | — | — | EP | claimed |