Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 2/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5771348 | 0.98 | NPY5R (0.46) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5773747 | 0.77 | NPY5R (0.51) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5774370 | 0.76 | NPY5R (0.50) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5776579 | 0.67 | NPY5R (0.72) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5771159 | 0.66 | RAB9A (0.42) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5771345 | 0.65 | NPY5R (0.69) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5773821 | 0.65 | RAB9A (0.44) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5773316 | 0.65 | NPY5R (1.00) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5773172 | 0.64 | KCNH2 (0.41) | NPY5RRAB9APRKCI | |
| Hydrochloric Acid SCHEMBL5774363 | 0.64 | NPY5R (0.97) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |