Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776756 | 0.75 | KDM4E (0.34) | DRD4 | |
| SCHEMBL5777367 | 0.71 | KDM4E (0.48) | DRD4 | |
| SCHEMBL5780720 | 0.69 | KDM4E (0.37) | DRD4 | |
| SCHEMBL5778123 | 0.67 | — | — | |
| SCHEMBL5814129 | 0.67 | ADORA2A (0.35) | — | |
| SCHEMBL5776724 | 0.61 | — | — | |
| SCHEMBL15991330 | 0.56 | ALDH1A1 (0.37) | — | |
| SCHEMBL5094067 | 0.55 | ALDH1A1 (0.37) | — | |
| SCHEMBL17076776 | 0.54 | ALDH1A1 (0.41) | — | |
| SCHEMBL2624132 | 0.54 | AURKA (0.39) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |