Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 5/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641568 | 1.00 | ALB (0.47) | ALBFBP1HRH4P4HBGRM5 | |
| SCHEMBL9641842 | 0.94 | ALB (0.46) | ALBFBP1HRH4P4HBGRM5 | |
| SCHEMBL9641837 | 0.94 | ALB (0.46) | ALBFBP1HRH4P4HBGRM5 | |
| SCHEMBL27569406 | 0.84 | LCK (0.43) | ALB | |
| SCHEMBL5778664 | 0.84 | LCK (0.43) | ALB | |
| SCHEMBL9260315 | 0.80 | ALB (0.49) | ALB | |
| SCHEMBL5777449 | 0.80 | ALB (0.49) | ALB | |
| SCHEMBL8304425 | 0.80 | ALB (0.52) | ALB | |
| SCHEMBL8304428 | 0.80 | ALB (0.52) | ALB | |
| SCHEMBL5775275 | 0.80 | ALB (0.52) | ALBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0287471-B1 | CARBOXYSTYRENE DERIVATIVES AND DRUGS CONTAINING THEM AS EFFECTIVE INGREDIENTS | MITSUBISHI KASEI CORPORATION (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-4925861-A | LEUKOTRIENE ANTAGONISTS, PHOSPHOLIPASE INHIBITORS | MITSUBISHI KASEI CORPORATION (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0287471-A2 | Carboxystyrene derivatives and drugs containing them as effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1988-10-19 | — | — | EP | disclosed |